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For laboratory research use only.) Selective NNMT inhibitor with documented IC values in preclinical biochemical assays (pmc.ncbi.nlm.nih.gov) Studied in diet-induced obese (DIO) mouse models for effects on adipose tissue and metabolic markers

By inhibiting this enzyme, 5-Amino-1MQ prevents the loss of these precursors, effectively redirecting them into the NAD+ salvage pathway

Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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